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Showing posts with the label prader

Treatment of Scoliosis in patients with Prader-Willi

ScoliosisJournal report: Treatment of scoliosis in patients affected with Prader-Willi syndrome using various different techniques Authors: Tiziana Greggi, Kostas Martikos, Francesco Lolli, Georgios Bakaloudis, Mario Di Silvestre, Alfredo Cioni, Giovanni Barbanti Brodano and Stefano Giacomini Background The incidence of spinal deformity in children with Prader-Willi syndrome (PWS) is high, with 86% of these patients found to have a significant structural scoliosis; however, there are very few case reports describing surgical treatment for this deformity. Methods The authors reviewed a case series consisting of 6 patients who underwent spine surgery for scoliosis. Children's mean age at first surgery was 12 years and 10 months (range, 10 to 15 yrs). Clinical evaluation revealed the typical phenotype of the PWS in all of the patients; 4 subjects had a karyotype confirmation of PWS. Major structural curves showed preoperative mean Cobb angles of 80.8degrees (range, ...

Scoliosis with Prader Willi Syndrome

Scoliosis journal reported comparisons of conservative and surgical treatment in patients with Scoliosis and Prade Willi Syndrome Authors: Hans-Rudolf Weiss and Deborah Goodall Abstract (provisional) Background In children with Prader Willi syndrome (PWS), besides growth hormone (GH) therapy, control of the food environment and regular exercise, surgical treatment of scoliosis deformities seems the treatment of choice, eventhough the risks of spinal surgery in this specific population is very high. Therefore the question arises as to whether the risks of spinal surgery outweigh the benefits in a condition, which bears significant risks per se. The purpose of this systematic review of the Pub Med literature was to find mid or long-term results of spinal fusion surgery in patients with PWS, and to present the conservative treatment in a case study of nine patients with this condition. Methods Types of studies included; all kinds of studies; retrospective and prospective ones, which r...